In short, what is the company?
We’re a contract research organization (CRO) offering Transmission Electron Microscopy (TEM), resin embedding, and Whole-Slide Imaging (WSI).
We have no minimums, no complex contracts, no bundles, no incomprehensible terms and conditions, no “gotchas”. We’re here to do what you need to reach your goal.
We are not dedicated to one industry. Pharmaceutical Industry, Education, Veterinary, Botany, Clinical, samples of Aliens from Mars….
If it can be embedded, sectioned, or examined by TEM, we’re interested!
Who is behind this company?
Hi! I’m Chris. 🙂
I’m the owner/founder/technician/scientist/study director/troubleshooter/shipping&receiving/HR/complaints department.
I am, however, not the billing department.
That’s my spouse.
We are a two-person operation in Stratham, New Hampshire, USA.
Are you really independent?
Yup. We are not affiliated with any university or other business entity. We own, under one roof, all of the equipment needed to take your samples from wet tissue to finished micrographs. We do not subcontract any work with the exception of written pathology reports. This allows us to take on projects that no other labs can, as we do not have shareholders, stock prices, lab managers, or department chairs to worry about.
We do not disclose our clients.
What’s your background?
I fell in love with electron microscopy as an undergrad, having been able to take both scanning and transmission electron microscopy courses. After a short stint in vaccine manufacturing, I landed my dream job in a preclinical electron microscopy lab at one of the Big Pharma’s. I’d spend the next 20 years there.
Life happens, though. In 2025 I left Big Pharma, but my love of TEM didn’t leave me. Though a series of unlikely events, the concept of starting an independent lab became reality.
I am a Certified Electron Microscopy Technologist though the Microscopy Society of America. Certification #2022.
I am not a veterinary pathologist, though. While I am adept at normal/not normal, we are partnered with a experienced veterinary pathologist if a written diagnosis is required for your needs.
What’s with the name?
Choosing a name for a company in 2025 is a trick.
To have meaning, and to have a reasonable-length and memorable .com address, takes some thinking.
We are not an all-purpose CRO that happens to do TEM and resin embedding.
All we do is TEM and resin embedding. I wanted the name to reflect our focus. Somehow.
We are long-time owners of hounds; we have three now. While I was ruminating on the name of this not-yet-a-company one evening, our Bluetick Hound, Miss Sugar-May, was snoring and drooling on my leg.
Hound Dog TEM it was, then.
No, we do not need a doorbell at home.
Publications?
Bond K, Klokman G, Xu Y, Wu X, Schustak J, Mandelbaum J, Twarog M, Han H, Aihara F, Paulina MK, Coble M, Hayden C, Galarneau JR, Demirs JT, Qiu Y, Esterberg R, Huang Q, Prasanna G, Wilson CW, Saint-Geniez M, Aranda J, Bao Y. Double-Stranded RNA Induces Retinal Pigment Epithelium Cell Degeneration and Inflammation. FASEB J. 2025 Aug 31;39(16):e70786. doi: 10.1096/fj.202402181R. PMID: 40814782.
Hayden CM, Meseck EK. Transmission Electron Microscopy of the Retina: A Method for Sample Preparation and Evaluation. Toxicologic Pathology. 2020;49(3):521-527. doi:10.1177/0192623320954124
Omar Delgado, Erika Lima, Natasha Buchanan, Hui Li, Joanna Vrouvlianis, Barrett Leehy, Chad E Bigelow, Junzheng Yang, Jean-Rene Galarneau, Emily Meseck, Christopher Hayden, Stephen H Poor, Sha-Mei Liao; Overexpression of HTRA1 in mice compromises the extracellular matrix integrity in Bruch’s membrane and choroidal/retinal vasculature. Invest. Ophthalmol. Vis. Sci. 2019;60(9):1233.
Collins A, Hayden C, Meseck EK. Transmission Electron Microscopy of the Peripheral Nervous System: Methods, Sample Preparation, and Case Studies. Toxicol Pathol. 2025 Nov 18:1926233251395683. doi: 10.1177/01926233251395683.